Antioxidants are Important for the Brain

Human brain

From your first moment to your last and for every microsecond in between, there is a war raging in every part of your body.  Literally millions of these battles happen at the same time with oxy-radicals on one side and antioxidants on the other. It’s a war that affects your lifespan, your vulnerability to many different diseases and without question the quality of your life and health as a senior.

A human brain is highly vulnerable to oxyradical damage because although it only accounts for about 2% of your body mass, about 20% of the oxygen you take in is metabolized in your brain.  Free or oxy-radicals – unstable oxygen molecules, are created by many different things, but a major  cause is a natural and unavoidable by-product of metabolizing oxygen. Since twenty percent of your oxygen supply is used by your brain, it’s easy to understand that the cells in your brain will be subjected to a high number of free radicals.

Within your brain is a large concentration of fat molecules known as Lipids. Lipids include sterols, waxes, fats and also include a few fat soluble vitamins like E, A, D and K. Lipids store energy. They are  signaling molecules and they’re structural components of your cell membranes.  Lipid peroxidation is the name given to free radical Lipid damage and a reason for the importance of antioxidant supplements to the health and functioning of your beloved bonce.

Your brain is defended against Lipid peroxidation by antioxidants, and at best from a group called Network Antioxidants or the Antioxidant Network. The network includes Vitamins C, E, CoEnzyme-Q10, glutathione and Lipoic acid.  Network Antioxidants function as a team to clear out free radicals in the brain and are also uniquely able to repair each other. 

Among the Network Antioxidants, the most important is Glutathione also known as The Master Antioxidant. Glutathione is naturally produced in your body and can be found in each and every cell.

Surprisingly, your brain maintains lower levels of the Master Antioxidant, Glutathione than do other organs and with aging, the total supply is further depleted because our ability to produce Glutathione falls by around ten percent with every decade after our twenties.  But your brain must have Glutathione to be healthy. 

There is a powerful correlation between Alzheimer’s and aluminum. In a study conducted in 2009 on laboratory rats, two equal groups were purposely given aluminum toxins, but one group was also supplied with free radical scavengers- antioxidants.  One group recorded a significant increase in lipid peroxidation that results in a condition known as oxidative stress. Reduced Glutathione and other network antioxidants were also noted. For the group that was provided with the toxins and the antioxidants, none of these changes were measured .

Because of it’s vulnerability to the creation of lipid peroxides a plentiful store of antioxidants (in particular Network Antioxidants and most importantly, Glutathione) is key to sustaining a healthy and functioning brain. While oral glutathione supplements are not considered to be effective, you can take a glutathione precursor like Max One.

Glutathione and the Antioxidant Network

Antioxidants are our body’s primary protection against the harm triggered by free radicals which contribute to many chronic inflammatory and degenerative problems. Oxy radicals are the root cause of premature aging. Among all the antioxidants, a group of five are acknowledged as Network Antioxidants. This group of both fat and water soluble antioxidants work together to assist your cells and do the job together to support each other.

How Network Antioxidants work

When an antioxidant passes an electron to correct or repair a free radical, it actually becomes one, but a benign one without the capacity to continue the chain reaction.  Unfortunately, when they become oxidized, antioxidants can no longer perform effectively.  But, what is unique about the network antioxidants is that are able to regenerate each other and carry on the cycle of searching out and repairing free radicals.

Even though they do the job together, the network antioxidants fulfill diverse jobs.  The fat soluble ones, namely CoQ-10 and Vitamin E protect the fatty cell wall and the cell mitochondria, while the water soluble antioxidants, Glutathione and Vitamin C protect the center of the cell. ALA – Alpha Lipoic Acid is unique in that it is both fat and water soluble.

Vitamin C is the link which joins the fat soluble and water soluble antioxidants in the network and is primarily responsible for rejuvenating Vitamin E when it becomes oxidized.

Vitamin E is closely aligned with heart disease prevention, because it’s the only antioxidant that can reach fatty parts of the cell that are not reachable to the rest of the network.  It’s actually not a single compound but is instead a group of fat soluble alcohols.

CoQ-10 or CoEnzyme Q-10 is present in all your cells, where it is concentrated in the mitochondria,  the component of your cell that creates energy. Mitochondria are susceptible to free radical injury which has been evidenced as a loss of energy as we age. Additionally, CoQ-10 contributes in the regeneration of Vitamins C, E and Glutathione.

Glutathione, popularly recognized as the Body’s Master antioxidant is continuall circulating through your cells, repairing your immune cells and cleansing cellular waste from your body. It supports the rejuvenation of all of the remaining network antioxidants. Raising your glutathione levels helps protect you from various inflammatory conditions, autoimmune diseases, chronic fatigue syndrome, asthma and others.

Alpha Lipoic Acid is unique amongst the Network Antioxidants in that it is both fat and water soluable and can help both the fatty membrane and water based interior of your cells. It is also uniquely capable of repairing itself and notably can regenerate the other network antioxidants including glutathione. It helps to avert muscle damage during tough workouts.

Like glutathione and CoEnzyme Q-10, ALA is created by your body, but the production capacity declines substantially as we age.

Antioxidants and Oxidative Stress

Elderly man in great shape

Presenting all the connections that exist between aging, DNA damage, chronic pain, inflammation,  oxidative stress, the role of antioxidants and our metabolism and immune systems is a long and very complex process.  However, there is a definite link between the prevention of oxidative stress and the avoidance or at least delayed onset of many degenerative and often painful illnesses that we expect to be a part of normal aging.

Oxidative stress is  a killer- even if it doesn’t sound like one and its associated with many conditions and diseases like  Alzheimer’s disease, Parkinson’s disease, myocardial infarction (a heart attack that prevents blocks the blood supply to a part of the heart muscle causing it to die) other forms of heart failure  and chronic fatigue syndrome.

Oxidative stress is the resulting condition when there is either an uncontrolled increase in peroxides and oxy-radicals/free radicals (collectively referred to as reactive oxygen species)  or a significant shortfall in the body’s antioxidant defense systems, one of which is glutathione.

When your body can’t use its supply of antioxidants to protect itself- at a cellular level- from oxy-radical damage, you have oxidative stress.

Reactive oxidative species originate in different ways – both internally and externally.

Externally, free radicals are caused by; introduced toxins and pathogens, cigarette smoke, pollution, chemotherapy, UV damage, radiation, vigorous exercise and stress.

Internally, oxy-radicals are a standard by-product of your metabolism.   Even our own immune system used oxy-radicals to defend us against toxins and pathogens.  Normally, our natural reserves of antioxidants will scavenge these damaging by-products.   However, when aging and/or poor health and nutrition interfere with our usual ability to prevent oxidative stress the damage builds up and our defenses are eventually overwhelmed.

Oxidative stress and reactive oxygen species are also responsible for damage DNA damage which can lead to mutation.  Unfortunately, just as our production of antioxidants like glutathione decreases as we age, so too does our natural ability to maintain our DNA in good repair. One obvious example of the damage caused oxidative stress is  aged appearance (at best) to the skin of people who have not been protected from the sun’s harmful rays.

According to the Free Radical Theory of Aging , the accumulation of damaged cells caused by the unchecked action of free radicals is a primary contributor to the process of aging and while we cannot stop that, no one will debate that good health practices can contribute to a increased quality of life through what are supposed to be the golden years.  Antioxidants like glutathione which you can support with supplements like MaxGXL® and MAXONE can also play a key role in the avoidance  of chronic inflammation by reducing oxidative damage.