Studies in Cell Transplantation show beneficial effects for variety of serious conditions

Studies in Cell Transplantation show beneficial effects for variety of serious conditions

Five studies from the current special issue of Cell Transplantation 24(4) devoted to work presented at the 21st meeting of the American Society for Neural Therapy and Repair (ASNTR) in 2014, a…
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National Institutes of Health (May 1, 2015): NIH Summit Delivers Recommendations to Transform Alzheimer’s Disease Research

Publication Date: 

Fri, 05/01/2015

The National Institutes of Health released recommendations today that provide a framework for a bold and transformative Alzheimer’s disease research agenda. Developed at the recent Alzheimer’s Disease Research Summit 2015: Path to Treatment and See Original Article

UNC Team uses cellular bubbles to deliver Parkinson's meds directly to brain

Pharmaceutical researchers at UNC are the first to use exosomes — lipid-and-protein spheres produced by cells — as vehicles to deliver a potent large-molecule drug to the brainResearchers…
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Harvard Gazette (May 5, 2015): 'New Clarity' Against Alzheimer's

Publication Date: 

Tue, 05/05/2015

The past year has been a hopeful one in the fight against Alzheimer’s disease. New findings have brought clarity to understanding the disease’s progress; new drugs to attack it are in trials.
Rudolph Tanzi, the Joseph P. and Rose F. Kennedy ProfesSee Original Article

Broad Institute (March 13, 2015): For Drivers of Alzheimer’s Disease, Check the Roadmap

Broad Institute (March 13, 2015): For Drivers of Alzheimer’s Disease, Check the Roadmap

Publication Date: 

Fri, 03/13/2015

Recently, the BroadMinded blog highlighted the exciting science emerging from the Roadmap Epigenomics program, resulting in the most comprehensive map of the human epigenome — the collection of chemical changes to DNA and its supporting proteins thaSee Original Article

National Institute on Aging (April 7, 2015): Nations Gather to Coordinate Global Dementia Research

Publication Date: 

Tue, 04/07/2015

NIA Director Dr. Richard J. Hodes joined health ministers, leading scientists, and advocates from around the world March 16-17 in Geneva, Switzerland, to advance dementia research planning on a global scale.

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Boston Globe (March 6, 2015): Older and Wiser? Some Brain Functions Improve as We Age

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Fri, 03/06/2015

There is hope for aging baby boomers.
The ability to recall names and faces with lightning speed may start to fade in one’s 20s, but our capability to perform other functions, such as learning new words, doesn’t peak until decades later, accordingSee Original Article

NTU scientists discover new treatment for dementia

New brain cells can be formed through deep brain stimulation, improving memory retentionPushing new frontiers in dementia research, Nanyang Technological University, Singapore (NTU Singapore)…
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New York Times (March 25, 2015): In Iceland's DNA, New Clues to Disease-Causing Genes

New York Times (March 25, 2015): In Iceland's DNA, New Clues to Disease-Causing Genes

Publication Date: 

Wed, 03/25/2015

Scientists in Iceland have produced an unprecedented snapshot of a nation’s genetic makeup, discovering a host of previously unknown gene mutations that may play roles in ailments as diverse as Alzheimer’s disease, heart disease and gallstones.See Original Article

Results announced from Phase 1 single ascending dose study of PRX002, a monoclonal antibody for the potential treatment of Parkinson's disease

Prothena Corporation plc, a late-stage clinical biotechnology company focused on the discovery, development and commercialization of novel protein immunotherapy programs, has announced positive…
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Mitochondria are altered in human cell model of Parkinson's disease

Buck Institute research provides tool for testing of potential therapeuticsBased on research in fruit flies, it has long been suspected that the most common mutation linked to both sporadic and…
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Migrating immune cells promote nerve cell demise in the brain

A small area in the midbrain known as the substantia nigra is the control center for all bodily movement.
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Washington Post (February 5, 2015): Alzheimer’s Costs Could Soar to $1 Trillion a Year by 2050, Report Says

Washington Post (February 5, 2015): Alzheimer’s Costs Could Soar to $1 Trillion a Year by 2050, Report Says

Publication Date: 

Thu, 02/05/2015

A report issued Thursday on the financial impact of Alzheimer’s disease in the United States warns that it could soar to more than $1 trillion a year by 2050, with much of it borne by the federal government, unless action is taken to shift current tSee Original Article

UCSF team finds key to making neurons from stem cells

Pnky, a noncoding RNA found in brain stem cells, may have a broad range of clinical applicationsA research team at UC San Francisco has discovered an RNA molecule called Pnky that can be…
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Finding points to possible mechanism underpinning Alzheimer's and Parkinson's diseases

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time discovered a killing mechanism that could underpin a range of the most intractable…
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Parkinson's gene linked to lung cancer

Researchers at the Medical College of Wisconsin (MCW), in collaboration with other colleagues of the Genetic Epidemiology of Lung Cancer Consortium (GELCC), have identified a gene that is associated…
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Hard-to-reach cancers targeted with 'Trojan horse' proteins

Hard-to-reach cancers targeted with 'Trojan horse' proteins

Scientists at Brunel University London have found a way of targeting hard-to-reach cancers and degenerative diseases using nanoparticles, but without causing the damaging side effects the treatment…
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New York Times (October 12, 2014): Breakthrough Replicates Human Brain Cells for Use in Alzheimer’s Research

Publication Date: 

Sun, 10/12/2014

For the first time, and to the astonishment of many of their colleagues, researchers created what they call Alzheimer’s in a Dish — a petri dish with human brain cells that develop the telltale structures of Alzheimer’s disease. In doing so, theSee Original Article

Parkinson's: small molecules researched for the regeneration of dopaminergic neurons

Researchers in the University of Helsinki plan to develop orally administrable small molecules that act similarly to neurotrophic factor GDNF.
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Penn study uncovers secrets of a clump-dissolving protein

Implications for new therapies for brain disorders involving misfolded proteins.
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New York Times (October 23, 2014): Can Video Games Fend Off Mental Decline?

New York Times (October 23, 2014): Can Video Games Fend Off Mental Decline?

Publication Date: 

Thu, 10/23/2014

“You just crashed a little bit,” Adam Gazzaley said.
It was true: I’d slammed my rocket-powered surfboard into an icy riverbank. This was at Gazzaley’s San Francisco lab, in a nook cluttered with multicolored skullcaps and wires that hooked upSee Original Article

New gene linked to blindness and Parkinson's diseases

The retinal pigment epithelium (RPE) is a tissue, which lines the back of the eye.
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Mechanism of Parkinson's spread demonstrated

Mechanism of Parkinson's spread demonstrated

An international, interdisciplinary group of researchers led by Gabor G. Kovacs from the Clinical Institute of Neurology at the MedUni Vienna has demonstrated, through the use of a new antibody…
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New gene linked to blindness and Parkinson's diseases

The retinal pigment epithelium (RPE) is a tissue, which lines the back of the eye.
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New findings on how brain handles tactile sensations

New findings on how brain handles tactile sensations

The traditional understanding in neuroscience is that tactile sensations from the skin are only assembled to form a complete experience in the cerebral cortex, the most advanced part of the brain.
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Computer model of nerve cells provides insights into communication problems in diseases of the brain

Study shows the interdependency between the structure and function of neuronsNerve cells communicate with each other via intricate projections.
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New York Times (October 12, 2014): Breakthrough Replicates Human Brain Cells for Use in Alzheimer’s Research

New York Times (October 12, 2014): Breakthrough Replicates Human Brain Cells for Use in Alzheimer’s Research

Publication Date: 

Sun, 10/12/2014

For the first time, and to the astonishment of many of their colleagues, researchers created what they call Alzheimer’s in a Dish — a petri dish with human brain cells that develop the telltale structures of Alzheimer’s disease. In doing so, theSee Original Article

Forbes (July 16, 2014): Can An Eye Test Predict Alzheimer's? Scientists Unveil New Vision Scans

Publication Date: 

Wed, 07/16/2014

A simple eye test could soon reveal whether you have Alzheimer’s Disease – or even if the disease looms in your future. In fact, according to trial results released this week, the vision test detected signs of Alzheimer’s 15 to 20 years before tSee Original Article

The cell recognizes the buildup of misfolded proteins, offers insight into Alzheimer's, ALS, Huntington's, Parkinson's, and type 2 diabetes

The cell recognizes the buildup of misfolded proteins, offers insight into Alzheimer's, ALS, Huntington's, Parkinson's, and type 2 diabetes

Living cells are like miniature factories, responsible for the production of more than 25,000 different proteins with very specific 3-D shapes.
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Forbes (July 14, 2014): Hard Evidence We Can Slow Alzheimer's By Exercising The Body And The Mind

Publication Date: 

Mon, 07/14/2014

Alzheimer’s disease is one of the most feared diagnoses among patients. It destroys people’s minds, their personalities, the very essence of who they are. And once the disease has been diagnosed, there is nothing modern medicine can do to stop it.See Original Article